How verapamil can help in peyronies disease Conclusion
If you are considering verapamil injections for Peyronie's disease, it's important to consult with a Urologist specialising in sexual medicine.
Urologists at Moorgate Andrology can provide a comprehensive evaluation, discuss treatment options, and create a personalized treatment plan based on individual needs and circumstances.
Studies on the effectiveness of verapamil for Peyronie's disease have produced mixed results. While some studies suggest that verapamil injections can lead to a reduction in penile curvature and improvement in symptoms for some individuals, others have shown modest benefits or no significant improvement at all. There is no guarantee that this treatment will work to improve the curvature, however studies show encouraging results and many patients look to try a non-surgical option before considering a surgical procedure as a last resort. Some surgical procedures such as the Nesbit procedure offered sometimes by the NHS, can lead to significant penile shortening. At Moorgate Andrology we also provide length sparing surgical procedures for peyronies disease at the most advanced level. Verapamil affords a chance to avoid surgery in some cases.
Whatever treatment is chosen the objective is to always try and restore sexual function.
How verapamil can help in peyronies disease
Reduction in Penile Curvature:
Some studies have reported a reduction in penile curvature with verapamil injections.
In a study published in the renowned Journal of Sexual Medicine, researchers found that 63% of patients treated with verapamil injections experienced a reduction in penile curvature of at least 20 degrees.
Another study published in the International Journal of Impotence Research reported that 75% of patients experienced an improvement in penile curvature after verapamil injections.
Improvement in Pain and Erectile Function:
Verapamil injections have also been associated with improvements in pain and erectile function for some individuals.
A study published in Urology found that 74% of patients experienced a reduction in penile pain after verapamil treatment.
Some studies have also suggested improvements in erectile function, although the results have varied.
Plaque Size and Hardness:
Verapamil is thought to work by breaking down the collagen fibres in the plaque, potentially reducing its size and hardness.
Studies have shown mixed results regarding the effect of verapamil on plaque size and hardness.
Treatment Duration and Success:
Verapamil injections are typically given in a series of six treatments, between two and four weeks apart.
The success of verapamil treatment can vary among individuals, with some experiencing significant improvements and others showing minimal changes. Those will relatively mild degrees of curvature will perhaps see objective improvement. If the curvature is significant then surgery maybe required to restore satisfactory sexual function.
Considerations and Limitations:
Verapamil injections are generally considered for individuals for whom the curvature that interferes with sexual activity. This means that the curvature make sexual intercourse difficult or painful.
Response to verapamil treatment can vary widely among patients, and not everyone will experience the same degree of improvement.
Verapamil injections are associated with potential side effects, including pain or discomfort at the injection site, bruising, swelling, and in rare cases, infection or allergic reactions.
Conclusion:
While verapamil injections have shown promise in some studies for reducing penile curvature, improving pain, and possibly softening plaques in Peyronie's disease, the overall effectiveness does very among individuals. It's essential to discuss potential risks, benefits, and expectations with our Urologist, Dr Nenad Djakovic, who is very experienced in treating Peyronie's disease. He can provide personalized guidance, discuss other treatment options, and help create a treatment plan tailored to individual needs and circumstances. A consultation can be provided remotely on video, with the benefit of photos of the penis in full erection in order to help with the assessment